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Legionella pneumophila type II secretome reveals a polysaccharide deacetylase that impacts intracellular infection, biofilm formation, and resistance to polymyxin- and serum-mediated killing
by Carlton O. AdamsJackson A. CampbellBeichang ZhangLeanne CleaverSarah B. BierJoshua MayoralRichard C. WhiteJames A. GarnettNicholas P. Cianciotto1Department of Microbiology and Immunology, Northwestern University Medical Schoolhttps://ror.org/000e0be47, Chicago, Illinois, USA2Centre for Host-Microbiome Interactions, Faculty of Dental, Oral & Craniofacial Sciences, King’s College Londonhttps://ror.org/0220mzb33, London, United KingdomFloyd L. Wormley on June 20, 2025 at 7:00 am
Activation of the Staphylococcus aureus intramembrane sensing histidine kinase SaeS via intramembrane interaction with the bacterially encoded small protein ScrA
by Marcus A. WittekindIan R. MonkRyan W. SteereEmily G. SudnickDonald HolzschuPadraig DeighanTimothy P. StinearRonan K. Carroll1Department of Biological Sciences, Ohio University110002, Athens, Ohio, USA2Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, The University of Melbourne198084https://ror.org/01ej9dk98, Parkville, Victoria, Australia3Department of Biology, Emmanuel College10645, Boston, Massachusetts, USA4Infectious and Tropical Disease Institute, Ohio University1354https://ror.org/01jr3y717, Athens, Ohio, USAKelly S. Doran on June 20, 2025 at 7:00 am
Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection
by Víctor R. Vázquez MarreroJessica DoernerKimberly A. WodzanowskiJenna ZhangAllyson LuFrankie D. BoyerIsabel VargasSuzana HossainKarly B. KammannMadison V. DreslerSunny Shin1Department of Microbiology, University of Pennsylvania, Perelman School of Medicine6572https://ror.org/00b30xv10, Philadelphia, Pennsylvania, USA2Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States3Belmont University5715https://ror.org/033vjpd42, Nashville, Tennessee, USA4Department of Biological Sciences, Mount Holyoke College7397https://ror.org/031z8pr38, South Hadley, Massachusetts, USACraig R. Roy on June 18, 2025 at 7:00 am
Quorum sensing mediates morphology and motility transitions in the model archaeon Haloferax volcanii
by Priyanka ChatterjeeCaroline E. ConsoliHeather SchillerKiersten K. WinterMonica E. McCallumStefan SchulzeMechthild Pohlschroder1Department of Biology, University of Pennsylvania171652, Philadelphia, Pennsylvania, USA2Department of Microbiology, Perelman School of Medicine, University of Pennsylvania332252, Philadelphia, Pennsylvania, USA3Department of Chemistry, University of Pennsylvania312071, Philadelphia, Pennsylvania, USA4College of Science, Gosnell School of Life Sciences, Rochester Institute of Technology173221, Rochester, New York, USADianne K. Newman on June 18, 2025 at 7:00 am
Will gut, oral, and vaginal microbiota influence the outcome of FET or be influenced by FET? A pilot study
by Zhao ZhangYiwen ZhangAihua WuChengfang XuZhe Li1Department of Reproduction, Southern Medical University Affiliate Dongguan People’s Hospital594334, Dongguan, Guangdong, China2Department of Obstetrics, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaRobert A. Bonomo on June 17, 2025 at 7:00 am
Ser/Thr phosphorylation of Mycobacterium tuberculosis type II RelK toxin by PknK destabilizes TA interaction and interferes with toxin neutralization
by Shafinaz Rahman SarahAbhishek GargSadiyah AfrozShaleen KorchArjun RayAmita GuptaVandana Malhotra1Department of Biochemistry, Sri Venkateswara College, University of Delhi208742, New Delhi, India2Department of Biochemistry, University of Delhi South Campus93081https://ror.org/04gzb2213, New Delhi, India3Department of Computational Biology, Indraprastha Institute of Information Technology243095https://ror.org/03vfp4g33, Delhi, India4Department of Pharmacology, Midwestern University3541https://ror.org/00t30ch44, Glendale, Arizona, USATarek MsadekPromod K. Mehta on June 17, 2025 at 7:00 am
The dual role of type I interferons in bacterial infections: from immune defense to pathogenesis
by Mingjie QiuJiayang LiWenqi WuJianan RenXiuwen Wu1Research Institute of General Surgery, Jinling Hospital, the Affiliated Hospital of Medical School, Nanjing Medical University12461https://ror.org/059gcgy73, Nanjing, Jiangsu, China2Research Institute of General Surgery, Jinling Hospital, the Affiliated Hospital of Medical School, Nanjing University12581https://ror.org/01rxvg760, Nanjing, Jiangsu, ChinaJorge E. Vidal on June 17, 2025 at 7:00 am
Assessment of the public health risk of novel reassortant H3N3 avian influenza viruses that emerged in chickens
by Han LiQi TongMengyan TaoJixiang LiHaili YuQiqi HanJiancheng WuRiguo LanJingjing HanHaoyu ChangYan LiJuan PuYipeng SunLitao LiuYajin QuQuanlin LiLu LuJinhua LiuHonglei Sun1National Key Laboratory of Veterinary Public Health and Safety, Key Laboratory for Prevention and Control of Avian Influenza and Other Major Poultry Diseases, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University630101, Beijing, Beijing, China2The Roslin Institute, University of Edinburgh15551https://ror.org/01920rj20, Edinburgh, Scotland, United KingdomJohn A. Lednicky on June 16, 2025 at 7:00 am
Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex
by Guido C. PaesenWeng M. NgSimon KimudaGeoff SuttonKatie J. DooresThomas A. Bowden1Division of Structural Biology, Centre for Human Genetics, University of Oxford6396https://ror.org/052gg0110, Oxford, United Kingdom2Research Complex at Harwell, Harwell Science and Innovation Campus70597, Harwell, United Kingdom3Electron Bio-Imaging Centre, Diamond Light Source120796https://ror.org/05etxs293, Didcot, United Kingdom4Kings College London, Department of Infectious Diseases, Guy’s Hospitalhttps://ror.org/04r33pf22, London, United KingdomSabra KleinFelix A. Rey on June 13, 2025 at 7:00 am
Live Malassezia strains from the mucosa of patients with ulcerative colitis: pathogenic potential and environmental adaptations
by Yong-Joon ChoSeung Yong ShinJuan YangHyo Keun KimPiyapat RintarhatMinji ParkMuhyeon SungKate LagreeDavid M. UnderhillDong-Woo LeeSohyeong ChoiChang Hwan ChoiChul-Su YangWon Hee Jung1Department of Molecular Bioscience, Kangwon National University34962https://ror.org/01mh5ph17, Chuncheon-si, South Korea2Multidimensional Genomics Research Center, Kangwon National University34962https://ror.org/01mh5ph17, Chuncheon-si, South Korea3Department of Internal Medicine, Chung-Ang University College of Medicinehttps://ror.org/01r024a98, Seoul, South Korea4Department of Systems Biotechnology, Chung-Ang Universityhttps://ror.org/01r024a98, Anseong, South Korea5Department of Molecular and Life Science, Hanyang Universityhttps://ror.org/046865y68, Ansan, South Korea6Center for Bionano Intelligence Education and Research, Ansan, South Korea7F. Widjaja Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Centerhttps://ror.org/02pammg90, Los Angeles, California, USA8Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Centerhttps://ror.org/02pammg90, Los Angeles, California, USA9Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of Californiahttps://ror.org/05t99sp05, Los Angeles, California, USA10Department of Biotechnology, Yonsei Universityhttps://ror.org/01wjejq96, Seoul, South Korea11Department of Medicinal and Life Science, Hanyang Universityhttps://ror.org/046865y68, Ansan, South KoreaAlexander Idnurm on June 13, 2025 at 7:00 am
A molecular conveyor belt-associated protein controls the rotational direction of the bacterial type 9 secretion system
by Abhishek TrivediJacob A. MiratskyEmma C. HendersonAbhishek SingharoyAbhishek Shrivastava1School of Life Sciences, Arizona State University69991https://ror.org/03efmqc40, Tempe, Arizona, USA2Biodesign Institute, Arizona State University43363https://ror.org/03efmqc40, Tempe, Arizona, USA3Center for Biological Physics, Arizona State University7864https://ror.org/03efmqc40, Tempe, Arizona, USA4School of Molecular Sciences, Center for Applied Structural Discovery, Arizona State University7864https://ror.org/03efmqc40, Tempe, Arizona, USAClay Fuqua on June 13, 2025 at 7:00 am
Outcomes of experimental infection of calves with swine influenza H3N2 virus
by Lei ShiYuekun LangSawrab RoyZhenyu ShenDipali GuptaChao DaiMuhammad Afnan KhalidWilliam J. MitchellShuping ZhangRichard WebbyJuergen RichtWenjun Ma1Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missourihttps://ror.org/02ymw8z06, Columbia, Missouri, USA2Department of Molecular Microbiology & Immunology, School of Medicine, University of Missourihttps://ror.org/02ymw8z06, Columbia, Missouri, USA3MU Center for Influenza and Emerging Infectious Diseases, University of Missouri14716https://ror.org/02ymw8z06, Columbia, Missouri, USA4Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri14716https://ror.org/02ymw8z06, Columbia, Missouri, USA5Department of Host-Microbe Interactions, St Jude Children's Research Hospital5417https://ror.org/02r3e0967, Memphis, Tennessee, USA6Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University5308https://ror.org/05p1j8758, Manhattan, Kansas, USAPeter Palese on June 12, 2025 at 7:00 am
Distinct survival strategies in oligotrophic and eutrophic ecotype Synechococcus-bacteria co-cultures under iron limitation and warming conditions
by Bowen HeYu WangMin XuDavid A. HutchinsFei-Xue FuXiaomin XiaRan DuanTa-Hui LinNianzhi JiaoQiang Zheng1State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Institute of Marine Microbes and Ecospheres, Xiamen University554979, Xiamen, China2Fujian Key Laboratory of Marine Carbon Sequestration, Xiamen University12466https://ror.org/00mcjh785, Xiamen, China3School of Marine Science and Engineering, Hainan University74629https://ror.org/03q648j11, Haikou, China4Department of Biological Sciences, University of Southern California118558https://ror.org/03taz7m60, Los Angeles, California, USA5Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College5116https://ror.org/03taz7m60, Fujian, China,6Department of Basic Medical Science, Xiamen Medical College, Institute of Respiratory Disease5116https://ror.org/03taz7m60, Xiamen, ChinaMaría Mercedes Zambrano on June 12, 2025 at 7:00 am
KSHV reprograms host RNA splicing via FAM50A to activate STAT3 and drive oncogenic cellular transformation
by Shenyu SunLing DingKarla PaniaguaXian WangYufei HuangMario A. FloresShou-Jiang Gao1Cancer Virology Program, University of Pittsburgh Medical Center Hillman Cancer Center6595, Pittsburgh, Pennsylvania, USA2Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine12317, Pittsburgh, Pennsylvania, USA3Integrative System Biology Program, University of Pittsburgh School of Medicine12317, Pittsburgh, Pennsylvania, USA4Department of Electrical and Computer Engineering, University of Texas at San Antonio551331https://ror.org/01kd65564, San Antonio, Texas, USA5Department of Medicine, University of Pittsburgh School of Medicine12317, Pittsburgh, Pennsylvania, USA6Department of Electrical and Computer Engineering, Swanson School of Engineering, University of Pittsburgh110071https://ror.org/01an3r305, Pittsburgh, Pennsylvania, USAThomas Shenk on June 12, 2025 at 7:00 am
Two novel Patescibacteria: Phycocordibacter aenigmaticus gen. nov. sp. nov. and Minusculum obligatum gen. nov. sp. nov., both associated with microalgae optimized for carbon dioxide sequestration from flue gas
by Lauren JonasYi-Ying LeeTsvetan BachvaroffRussell T. HillYantao Li1Institute of Marine and Environmental Technology145781, Baltimore, Maryland, USA2University of Maryland Center for Environmental Sciencehttps://ror.org/04dqdxm60, Baltimore, Maryland, USAStephen J. Giovannoni on June 12, 2025 at 7:00 am
Toroidal displacement of Klebsiella pneumoniae by Pseudomonas aeruginosa is a unique mechanism to avoid competition for iron
by Diana PradhanAjay TanwarJoshua WongSrividhya ParthasarathiGad M. FrankelVarsha Singh1Department of Developmental Biology & Genetics, Indian Institute of Science29120https://ror.org/05j873a45, Bangalore, India2Division of Moleculer Microbiology, University of Dundee, Dundee, United Kingdom3Department of Life Sciences, Imperial College98455https://ror.org/041kmwe10, London, United Kingdom4Department of Physics, Indian Institute of Science534309https://ror.org/04dese585, Bangalore, IndiaKalai MatheeLars E. P. Dietrich on June 11, 2025 at 7:00 am
CCR2 recruits monocytes to the lung, while CX3CR1 modulates positioning of CD11cpos cells in the lymph node during pulmonary tuberculosis
by Alexander MohapatraBrian A. NorrisZachary HowardJoel D. Ernst1Division of Experimental Medicine, Department of Medicine, University of Californiahttps://ror.org/05t99sp05, San Francisco, California, USA2Division of Infectious Diseases, New York University School of Medicine12296, New York, New York, USASabine Ehrt on June 11, 2025 at 7:00 am
Exploration of virulence and immune evasion functions of the candidate vaccine antigen SpyAD in the globally disseminated M1T1 group A Streptococcus strain
by Alexandra StreamSamira DaheshLamar ThomasNina J. GaoElisabet BjånesKalisa KangTruman KohNeeraj KapoorVictor Nizet1Medical Scientist Training Program, University of California, San Diego School of Medicine12220, La Jolla, California, USA2Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego School of Medicine12220https://ror.org/0168r3w48, La Jolla, California, USA3Vaxcyte, Inc.681082, San Carlos, California, USA4Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego School of Medicine12220https://ror.org/0168r3w48, La Jolla, California, USAGerald B. Pier on June 11, 2025 at 7:00 am
Targeting the interaction between long noncoding RNA XR_001779380 and Prdm1 to enhance IFN-γ immunity in murine neonatal intestinal epithelial cells
by Kehua JinAi-Yu GongShuhong WangGislaine A. MartinsJuliane K. Strauss-SoukupRoberta M. O'ConnorXian-Ming Chen1Department of Microbial Pathogens and Immunity, Rush University Medical Center2468https://ror.org/01j7c0b24, Chicago, Illinois, USA2Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Hubei University of Science and Technology418442https://ror.org/018wg9441, Xianning, Hubei, China3Departments of Medicine and Biomedical Sciences, Research Division of Immunology Cedars-Sinai Medical Center, David Geffen School of Medicine, University of California—Los Angeles8783https://ror.org/046rm7j60, Los Angeles, California, USA4Department of Chemistry and Biochemistry, Creighton University College of Arts and Sciences357852https://ror.org/05wf30g94, Omaha, Nebraska, USA5Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota70195, St. Paul, Minnesota, USALaura J. Knoll on June 11, 2025 at 7:00 am
Isolation and characterization of mollicute symbionts from a fungus-growing ant reveals high niche overlap leading to co-exclusion
by Emily A. GreenIan KlepackiJonathan L. Klassen1Department of Molecular and Cell Biology, University of Connecticut124501, Storrs, Connecticut, USA2Emerging Pests and Pathogens Research USDA-ARS, Ithaca, New York, USA3Institute for Systems Genomics, University of Connecticuthttps://ror.org/02der9h97, Storrs, Connecticut, USAKatherine P. Lemon on June 10, 2025 at 7:00 am