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The Saccharomyces killer toxin K62 is a protein of the aerolysin family
by Jack W. CreaghMichael RolfsmeierKasen J. EvansRodolfo BizarriaDavid C. ReetzTanner J. BadigianLance R. FredericksAva M. HasenoehrlAbigail P. BrownBrayden M. GravesConnor K. AlexanderAndre RodriguesEric P. StoffregenJagdish Suresh PatelF. Marty YtrebergPaul A. Rowley1Department of Biological Sciences, University of Idaho123394https://ror.org/03hbp5t65, Moscow, Idaho, USA2Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulohttps://ror.org/036rp1748, Ribeirão Preto, Brazil3Physical, Life, Movement & Sport Sciences Division, Lewis-Clark State College4522https://ror.org/038x7ta12, Lewiston, Idaho, USA4Department of Chemical and Biological Engineering, University of Idaho681878https://ror.org/03hbp5t65, Moscow, Idaho, USA5Institute for Modeling Collaboration and Innovation, University of Idaho5640https://ror.org/03hbp5t65, Moscow, Idaho, USA6Department of Physics, University of Idaho5640https://ror.org/03hbp5t65, Moscow, Idaho, USA7Institute of Ocean and Earth Sciences, Universiti Malaya, C308, Institute of Advanced Studies Building, Kuala Lumpur, MalaysiaChris Todd Hittinger on November 11, 2025 at 8:00 am
Plasmid transmission dynamics and evolution of partner quality in a natural population of Rhizobium leguminosarum
by David Vereau GorbitzChase P. SchwarzJohn G. McMullenMario Cerón-RomeroRebecca T. DoyleJennifer A. LauRachel J. WhitakerCarin K. VanderpoolKaty D. Heath1Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaignhttps://ror.org/047426m28, Urbana, Illinois, USA2Department of Microbiology, University of Illinois Urbana-Champaign14589https://ror.org/047426m28, Urbana, Illinois, USA3Department of Plant Biology, University of Illinois Urbana-Champaign14589https://ror.org/047426m28, Urbana, Illinois, USA4Department of Biology, Indiana University1772https://ror.org/01kg8sb98, Bloomington, Indiana, USA5Department of Biology, Case Western Reserve University2546https://ror.org/051fd9666, Cleveland, Ohio, USA6Department of Biology, McMaster University3710https://ror.org/02fa3aq29, Hamilton, Canada7Department of Plant and Microbial Biology, University of Minnesota Twin Cities, St. Paul, Minnesota, United StatesYunn-Hwen Gan on November 10, 2025 at 8:00 am
Human-specific activation of the DUX4-SLC34A2 axis by herpesviruses suppresses antiviral innate immunity
by Ming GaoXi ChengChuchu ZhangJiali MaXuezhang TianShaowei WangXiaoyu XieYunhong ZhongSiyuan WangPinghui FengJunjie Zhang1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, State Key Laboratory of Virology, Medical Research Institute, Wuhan University619779, Wuhan, China2Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University619779, Wuhan, China3Hubei Key Laboratory of Tumor Biological Behavior, Hubei Province Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University89674https://ror.org/01v5mqw79, Wuhan, China4Department of Colorectal and Anal Surgery, Clinical Center of Intestinal and Colorectal Diseases of Hubei Province, Zhongnan Hospital of Wuhan University89674https://ror.org/01v5mqw79, Wuhan, China5Hubei Key Laboratory of Intestinal and Colorectal Diseases, Zhongnan Hospital of Wuhan University89674https://ror.org/01v5mqw79, Wuhan, China6Section of Infection and Immunity, Herman Ostrow School of Dentistry, Norris Comprehensive Cancer Center, University of Southern California5116https://ror.org/03taz7m60, Los Angeles, USABlossom Damania on November 10, 2025 at 8:00 am
Phospho-mimetic CheV interacts with a subset of chemoreceptors
by Miguel A. MatillaMario Cano-MuñozElizabet Monteagudo-CascalesTino Krell1Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicashttps://ror.org/00drcz023, Granada, SpainMichael T. Laub on November 10, 2025 at 8:00 am
mGem: Immune recognition and clearance of bacteriophages—implications for phage therapy
by H. T. LeG. AhlenstielC. VenturiniS. A. Read1Blacktown Clinical School, Western Sydney University522514https://ror.org/0384j8v12, Sydney, New South Wales, Australia2Storr Liver Centre, Westmead Institute for Medical Researchhttps://ror.org/04zj3ra44, Sydney, New South Wales, Australia3Blacktown Mt Druitt Hospital, Sydney, New South Wales, Australia4Centre for Infectious Diseases and Microbiology (CIDM), Westmead Institute for Medical Research, Sydney, New South Wales, Australia5Sydney School of Veterinary Science, Faculty of Science, University of Sydney98482https://ror.org/0384j8v12, Sydney, New South Wales, AustraliaVinayaka R. Prasad on November 5, 2025 at 8:00 am
Plasmid replication initiator protein TrfA represses the host type III secretion system in Pseudomonas aeruginosa
by Yu ZhangLiwen YinQi LiuLepeng WangChenyu ShenYifan BianZhenzhen MaUn-Hwan HaZhihui ChengWeihui WuShouguang JinYongxin Jin1State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University616162https://ror.org/01y1kjr75, Tianjin, China2Department of Biotechnology and Bioinformatics, Korea University65692, Sejong, Republic of KoreaScot P. Ouellette on November 5, 2025 at 8:00 am
Systematic analysis of nutrient-microbiome interactions and their effects on host phenotypes in Drosophila
by Yi-Ting HungShu-Jen TuanAdam Chun-Nin Wong1Department of Entomology, National Chung Hsing Universityhttps://ror.org/03e29r284, Taichung, Taiwan, Republic of China2Department of Entomology and Nematology, University of Floridahttps://ror.org/02y3ad647, Gainesville, Florida, USA3Genetics Institute, University of Floridahttps://ror.org/02y3ad647, Gainesville, Florida, USAKatrine Whiteson on November 5, 2025 at 8:00 am
Tradeoffs in viral fitness driven by alternative entry pathways
by Marc Carrascosa-SàezJérémy DuflooRafael Sanjuán1Institute for Integrative Systems Biology (I2SysBio), University of Valencia – CSIC253325https://ror.org/043nxc105, Paterna, SpainChristian Drosten on November 5, 2025 at 8:00 am
LPS O-antigen polysaccharide length impacts outer membrane permeability of enteric gram-negative bacteria
by Kerrie L. MayTatsuya AkiyamaBella G. ParkerMinsu KimMarcin Grabowicz1Department of Microbiology and Immunology, Emory University School of Medicine12239https://ror.org/02gars961, Atlanta, Georgia, USA2Emory Antibiotic Resistance Center, Emory University School of Medicine12239https://ror.org/02gars961, Atlanta, Georgia, USA3Department of Physics, Emory University373618https://ror.org/018rbev86, Atlanta, Georgia, USA4Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine12239https://ror.org/02gars961, Atlanta, Georgia, USAM. Stephen Trent on November 5, 2025 at 8:00 am
Erratum for Dinh et al., “The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir”
by Tung DinhZahira TberJuan S. ReySeema MengshettiArun S. AnnamalaiReed HaneyLorenzo BrigantiFranck AmblardJames R. FuchsPeter CherepanovKyungjin KimRaymond F. SchinaziJuan R. PerillaBaek KimMamuka Kvaratskhelia on November 4, 2025 at 8:00 am
PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13
by Jinxiu LouHuixin ZhuZhen YangPing JiangGongguan LiuXianwei Wang1Key Laboratory of Animal Disease Diagnostics and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University70578https://ror.org/05td3s095, Nanjing, China2Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, ChinaLing Zhao on November 4, 2025 at 8:00 am
The cryptic diversity of hepadnavirus relatives
by Zhen GongGuan-Zhu Han1College of Life Sciences, Nanjing Normal University224704https://ror.org/036trcv74, Nanjing, Jiangsu, ChinaEugene V. Koonin on November 4, 2025 at 8:00 am
Two glycoside hydrolases decompose the sporangium matrix to release spores during sporangium dehiscence in Actinoplanes missouriensis
by Kyota MitsuyamaShixuan HuNaoki SunagawaKiyohiko IgarashiTakeaki TezukaYasuo Ohnishi1Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo13143https://ror.org/057zh3y96, Bunkyo-ku, Tokyo, Japan2Department of Biomaterial Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo13143https://ror.org/057zh3y96, Bunkyo-ku, Tokyo, Japan3Collaborative Research Institute for Innovative Microbiology, The University of Tokyo13143https://ror.org/057zh3y96, Bunkyo-ku, Tokyo, JapanArash Komeili on November 4, 2025 at 8:00 am
Functional insight into cyclin-dependent kinase (CDK)7 via chemical inhibition of the priority fungal pathogen Cryptococcus neoformans
by Pooja SethiyaDesmarini DesmariniBethany Grace BowringKyle CesarMichael J. BoucherAngela L. WeiHiten D. MadhaniBen CrossettAngela ConnellyCatriona L. HallidaySharon C.-A. ChenJoey LaiKoon Ho WongJulianne Teresa Djordjevic1Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research107640https://ror.org/04zj3ra44, Westmead, New South Wales, Australia2Faculty of Medicine and Health, Sydney Institute for Infectious Diseases, University of Sydneyhttps://ror.org/0384j8v12, Camperdown, New South Wales, Australia3Department of Biochemistry and Biophysics, University of California117253, San Francisco, California, USA4Sydney Mass Spectrometry, University of Sydneyhttps://ror.org/0384j8v12, Camperdown, New South Wales, Australia5Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology, Westmead Hospitalhttps://ror.org/04gp5yv64, Westmead, New South Wales, Australia6Westmead Hospital8539https://ror.org/04gp5yv64, Westmead, New South Wales, Australia7Scientific Platforms, Westmead Institute for Medical Researchhttps://ror.org/04zj3ra44, Westmead, New South Wales, Australia8Faculty of Health Sciences, University of Macauhttps://ror.org/01r4q9n85, Macau SAR, ChinaYong-Sun Bahn on October 31, 2025 at 7:00 am
Lactobacillus plantarum Lac16 alleviates dextran sodium sulfate-induced colitis in mice by suppressing NLRP3 inflammasome overactivation through microbiota-derived isobutyric acid
by Yuanhao ZhouBaikui WangQi WangFei WangXiaozhou MouLi GongWeifen Li1Department of Rehabilitation Medicine, Center for Rehabilitation Medicine, Rehabilitation and Sports Medicine Research Institute of Zhejiang Province, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College117839https://ror.org/05gpas306, Hangzhou, Zhejiang, China2Zhejiang Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine, Clinical Research Institute, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College117839https://ror.org/05gpas306, Hangzhou, Zhejiang, China3Key Laboratory of Molecular Animal Nutrition of the Ministry of Education, Institute of Animal Nutrition and Feed Sciences, College of Animal Sciences, Zhejiang University366125https://ror.org/00a2xv884, Hangzhou, China4Key Laboratory of Animal Nutrition and Feed Science (Eastern of China) of the Ministry of Agriculture, Institute of Animal Nutrition and Feed Sciences, College of Animal Sciences, Zhejiang University, Hangzhou, China5Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Institute of Animal Nutrition and Feed Sciences, College of Animal Sciences, Zhejiang University, Hangzhou, China6MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University12377https://ror.org/00a2xv884, Hangzhou, China7Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Scienceshttps://ror.org/00f809463, Hangzhou, China8Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University118208, Foshan, ChinaYung-Fu Chang on October 31, 2025 at 7:00 am
Toxoplasma effector TgWIP hijacks dendritic cell actin and motility via Nck1/Grb2 and the WAVE complex
by Pavel MoralesDaniel A. KramerCaroline de Moraes de SiqueiraAbbigale J. BrownLamba Omar SangaréBaoyu ChenJeroen P. J. Saeij1Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California8789https://ror.org/05rrcem69, Davis, California, USA2Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University1177https://ror.org/04rswrd78, Ames, Iowa, USA3Departments of Internal Medicine and Biophysics, University of Texas Southwestern Medical Center12334https://ror.org/05byvp690, Dallas, Texas, USALaura J. Knoll on October 31, 2025 at 7:00 am
Structural insight into RNA encapsidation by the severe fever with thrombocytopenia syndrome virus nucleocapsid protein
by Yong WangHao WuJiawen SunWenhua KuangHualin WangYun-Jia NingZengqin Deng1State Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences74614https://ror.org/01jxjav08, Wuhan, Hubei, China2University of Chinese Academy of Sciences74519, Beijing, China3Hubei Jiangxia Laboratory, Wuhan, Hubei, ChinaEdward W. Yu on October 31, 2025 at 7:00 am
The Candida albicans transcription factor Efg1 governs hyphal morphogenesis independently of the cAMP-protein kinase A pathway
by Juraj KramaraRohan S. WakadeCorey FrazerMark A. StamnesRichard J. BennettDamian J. Krysan1Department of Pediatrics, Carver College of Medicine, University of Iowa4083https://ror.org/036jqmy94, Iowa City, Iowa, USA2Department of Molecular Microbiology and Immunology, Brown University6752https://ror.org/05gq02987, Providence, Rhode Island, USA3Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa4083https://ror.org/036jqmy94, Iowa City, Iowa, USAMarcio Rodrigues on October 31, 2025 at 7:00 am
Genetic analysis of the NifM dependence of the nitrogenase iron proteins
by Zhuoting XieShuyi CaiHaoyang ChenShuyuan KongLetian TangYi-Ping WangJianguo Yang1State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking University12465https://ror.org/02v51f717, Beijing, China2College of Plant Protection, China Agricultural University539443, Beijing, China3College of Biological Sciences and Technology, Beijing Forestry University12380https://ror.org/04xv2pc41, Beijing, China4Yazhouwan National Laboratory735983, Sanya, ChinaArash Komeili on October 31, 2025 at 7:00 am
Sinorhizobium meliloti BR-bodies promote fitness during host colonization
by Kaveendya S. MallikaarachchiJason L. HuangShanmukha MadrasRodrigo A. CuellarZhenzhong HuangAlisa GegaImalka W. Rathnayaka-MudiyanselageVidhyadhar NandanaNadra Al-HusiniNatalie Saldaña-RiveraLoi H. MaEric NgKlara ChristensenNima PendarSophia LiNayeli Rodas DeleonJoseph C. ChenJared M. Schrader1Department of Biology, Indiana University1772https://ror.org/01kg8sb98, Bloomington, Indiana, USA2Departments of Chemistry and Biological Sciences, Wayne State University2954https://ror.org/01070mq45, Detroit, Michigan, USA3Department of Biology, San Francisco State University7147https://ror.org/05ykr0121, San Francisco, California, USAArash Komeili on October 31, 2025 at 7:00 am