Journal of Virology

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CD317 functions as a key antiviral factor in human herpesvirus 6 (HHV-6) infection
by Xianyi XuMinmin SongXin ZhangJunli JiaShuhua ChenHua XieLingyun LiJingjing MaHuamin Tang1Department of Immunology, National Vaccine Innovation Platform, School of Basic Medical Sciences, Nanjing Medical University12461https://ror.org/059gcgy73, Nanjing, China2Department of Critical Care Medicine, Changzhou Cancer Hospital162737https://ror.org/05psp9534, Changzhou, China3Jintan Hospital Affiliated to Jiangsu University, Changzhou, China4Department of Medical Genetics, Nanjing Medical University12461https://ror.org/059gcgy73, Nanjing, China5Department of Clinical Laboratory, Children’s Hospital of Nanjing Medical Universityhttps://ror.org/04pge2a40, Nanjing, China6The Laboratory Center for Basic Medical Sciences, Nanjing Medical University12461https://ror.org/059gcgy73, Nanjing, ChinaAnna Ruth Cliffe on June 24, 2025 at 7:00 am
CypA inhibits respiratory syncytial virus (RSV) replication by suppressing glycolysis through the downregulation of PKM2 expression
by Jing ZhangMiao LiJing ChengYutong WangCuiqing MaLizheng YinJiachao WangXue GaoWenzhang LiangLin Wei1Department of Immunology, Hebei Medical University12553https://ror.org/04eymdx19, Shijiazhuang, Hebei, China2Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, Hebei, China3Department of Immunology and Pathogen Biology, Hebei University of Chinese Medicine441322https://ror.org/02qxkhm81, Shijiazhuang, Hebei, China4Department of Pathogen Biology, Hebei Medical University12553https://ror.org/04eymdx19, Shijiazhuang, Hebei, ChinaAnice C. Lowen on June 24, 2025 at 7:00 am
The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women
by Sherazaan D. IsmailShorok SebaaBianca AbrahamsMartha C. NasonMitchell J. MumbyJimmy D. DikeakosSarah B. JosephMatthew MoeserRonald SwanstromNigel GarrettCarolyn WilliamsonThomas C. QuinnMelissa-Rose AbrahamsAndrew D. Redd1Institute of Infectious Disease and Molecular Medicine, University of Cape Town37716https://ror.org/03p74gp79, Cape Town, South Africa2Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, NIH656595https://ror.org/043z4tv69, Bethesda, Maryland, USA3Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University468153https://ror.org/02grkyz14, London, Ontario, Canada4Department of Microbiology and Immunology, University of North Carolina at Chapel Hill318275https://ror.org/0130frc33, Chapel Hill, North Carolina, USA5Lineberger Comprehensive Cancer Centre, University of North Carolina at Chapel Hill169113https://ror.org/0130frc33, Chapel Hill, North Carolina, USA6Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill196289https://ror.org/0130frc33, Chapel Hill, North Carolina, USA7Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal56394https://ror.org/04qzfn040, Durban, South Africa8Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal574009https://ror.org/04qzfn040, Durban, South Africa9National Health Laboratory Services of South Africa70685https://ror.org/00znvbk37, Johannesburg, South Africa10Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine229385https://ror.org/00za53h95, Baltimore, Maryland, USA11Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH469049https://ror.org/043z4tv69, Bethesda, Maryland, USAViviana Simon on June 24, 2025 at 7:00 am
Enterovirus C recombination groups: RNA sequence similarity and the viral polymerase underpin sexual replication mechanisms
by Evan M. OkolovitchVishnu GovindarajanRefugio Robles-SikisakaGrace CampagnolaBrian J. KempfAndrew L. RouthOlve B. PeersenDavid J. Barton1Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus129263https://ror.org/03wmf1y16, Aurora, Colorado, USA2Department of Biochemistry and Molecular Biology, Colorado State University548293, Fort Collins, Colorado, USA3Department of Immunology and Microbiology, Scripps Research4356https://ror.org/02dxx6824, La Jolla, California, USAStacey Schultz-Cherry on June 24, 2025 at 7:00 am
METTL3 regulates PRRSV replication by suppressing interferon beta through autophagy-mediated IKKε degradation
by Yunyun ZhaiLucai WangLijie LvXuyang ZhaoMengjie LiJiajing TianXiangqi QiuLulu YaoWenhui ZhuYunzhe KangAngke ZhangGuoqing ZhuangAijun Sun1International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University731518https://ror.org/04eq83d71, Zhengzhou, China2Longhu Laboratory of Advanced Immunology12636https://ror.org/04ypx8c21, Zhengzhou, China3Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, Henan Agricultural University70573https://ror.org/04eq83d71, Zhengzhou, ChinaRebecca Ellis Dutch on June 23, 2025 at 7:00 am
Zika virus non-structural protein NS2A mediated endoplasmic reticulum stress through interacting with Sarco/endoplasmic reticulum Ca2+-ATPase 2
by Shan WangShanshan TangYuxin ZhouQifei AnMengxing DuXiujuan YangPeng ZouLi TangYufeng Yu1Shanxi Key Laboratory of Functional Proteins, School of Basic Medical Sciences and Pharmacy, Shanxi Medical University74648https://ror.org/0265d1010, Taiyuan, China2Department of Public Health Laboratory Sciences, School of Public Health, Shanxi Medical University572534https://ror.org/0265d1010, Taiyuan, China3Shanghai Public Health Clinical Center, Fudan University12478https://ror.org/013q1eq08, Shanghai, ChinaShan-Lu Liu on June 23, 2025 at 7:00 am
The SHFV nsp2 and nucleocapsid proteins recruit G3BP1 to sites of viral replication, but stress granules are not induced by the infection
by Ayisha A. LavenderOreoluwa SolankeHsin-Yao TangHannah E. PeckDaryll VanoverPhilip J. SantangeloMargo A. Brinton1Department of Biology, Georgia State University1373https://ror.org/03qt6ba18, Atlanta, Georgia, USA2Ellen and Ronald Caplan Cancer Center, The Wistar Institute36586https://ror.org/04wncat98, Philadelphia, Pennsylvania, USA3Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University School of Medicine189277https://ror.org/02j15s898, Atlanta, Georgia, USAStacey Schultz-Cherry on June 23, 2025 at 7:00 am
Efficacy of oncolytic virus in the treatment of intermediate-to-advanced solid tumors: a systematic review and meta-analysis
by Jin-Zhou XuJian-Xuan SunChen-Qian LiuRuo-Yan PanNa ZengSi-Han ZhangYe AnMeng-Yao XuXing-Yu ZhongSi-Yang MaHao-Dong HeJia HuShao-Gang WangQi-Dong Xia1Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology12403https://ror.org/00p991c53, Wuhan, ChinaKoenraad van Doorslaer on June 20, 2025 at 7:00 am
Diversity and evolutionary history of RNA viruses among different horseshoe crab species
by Yu-Hua QiZhuang-Xin YeKe-Hui FengXiao-Wan MaChuan-Xi ZhangMeng-Hong HuMang ShiJian-Ping ChenJun-Min Li1State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Key Laboratory of Biotechnology in Plant Protection of Ministry of Agriculture and Zhejiang Province, Institute of Plant Virology, Ningbo University47862https://ror.org/03et85d35, Ningbo, China2Key Laboratory of Tropical Marine Ecosystem and Bioresource, Ministry of Natural Resources, Fourth Institute of Oceanography635955, Beihai, China3International Research Center for Marine Biosciences, Ministry of Science and Technology, Shanghai Ocean University74595https://ror.org/04n40zv07, Shanghai, China4Marine Biomedical Science and Technology Innovation Platform of Lin-gang Special Area, Shanghai, China5The Centre for Infection and Immunity Studies, School of Science, Shenzhen Campus of Sun Yat-sen University660329, Shenzhen, China6State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-Sen University26469, Guangzhou, ChinaMonique M. van Oers on June 20, 2025 at 7:00 am
Molecular mechanism of potently neutralizing human monoclonal antibodies against severe fever with thrombocytopenia virus infection
by Chuansong QuanKaixiao NieDezhen MaChao SuLianfeng LiWenjun ZhengChunhong YinYiwen WangPeipei YangDingkun PengXin LiuWeiwei LiWeixiao LiuChao ShanJie ZhengDi LiuHong ZhangMichael J. CarrGeorge F. GaoJianxun QiWeifeng Shi1Key Laboratory of Emerging Infectious Diseases in Universities of Shandong, Shandong First Medical University & Shandong Academy of Medical Scienceshttps://ror.org/05jb9pq57, Ji'nan, China2Department of Hematology, The Second Affiliated Hospital of Shandong First Medical University, Taian, China3School of Public Health, Shandong First Medical University & Shandong Academy of Medical Scienceshttps://ror.org/05jb9pq57, Ji'nan, China4Department of Vector Control, Taian Center for Disease Control and Preventionhttps://ror.org/05nda1d55, Taian, China5Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Advanced Institute for Life and Health, Southeast Universityhttps://ror.org/02ets8c94, Nanjing, China6State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences111613, Harbin, China7Infectious Disease Control Institute, Shandong Center for Disease Control and Prevention, Shandong Provincial Key Laboratory of Infectious Disease Prevention and Controlhttps://ror.org/027a61038, Ji'nan, China8State Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences74614, Wuhan, China9Shanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine56694https://ror.org/0220qvk04, Shanghai, China10CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences85387https://ror.org/02p1jz666, Beijing, China11Department of Infectious Disease Prevention and Control, Taian Center for Disease Control and Preventionhttps://ror.org/05nda1d55, Taian, China12Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences74614, Wuhan, China13National Virus Reference Laboratory, School of Medicine, University College Dublin37438https://ror.org/05m7pjf47, Dublin, Ireland14International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University12810https://ror.org/02e16g702, Sapporo, Japan15Ruijin Hospital, Shanghai Jiao Tong University School of Medicine56694https://ror.org/0220qvk04, Shanghai, ChinaJae U. Jung on June 20, 2025 at 7:00 am
UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L maturation
by Yongjun ChenYujin ShiXiaoyan ZuoXiaojing DongXia XiaoLan ChenZichun XiangLili RenZhuo ZhouWensheng WeiXiaobo LeiJianwei Wang1NHC Key Laboratory of System Biology of Pathogens, Christophe Mérieux Laboratory National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical Collegehttps://ror.org/02drdmm93, Beijing, China2Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College) Ministry of Education127394https://ror.org/00see0y83, Beijing, China3State Key Laboratory of Common Mechanism Research for Major Diseases, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College570570https://ror.org/02szepc22, Suzhou, Jiangsu, China4Biomedical Pioneering Innovation Center, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University117978https://ror.org/02v51f717, Beijing, ChinaShan-Lu Liu on June 18, 2025 at 7:00 am
Cellular miRNAs and viruses: trends in miRNA sequestering and target de-repression
by Bonita H. PowellKenneth W. WitwerMollie K. Meffert1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine1466https://ror.org/00za53h95, Baltimore, Maryland, USA2Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine1500https://ror.org/00za53h95, Baltimore, Maryland, USA3Department of Neurology, Johns Hopkins University School of Medicine1500https://ror.org/00za53h95, Baltimore, Maryland, USA4Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine1500https://ror.org/00za53h95, Baltimore, Maryland, USAHerman W. Favoreel on June 18, 2025 at 7:00 am
In vitro and in vivo characterization of a bat merbecovirus with ACE2- and DPP4-independent cell entry
by Hiromichi MatsugoTomoya KitamuraNaohiro TakahashiJames ChambersAyano IchikawaMisa KatayamaKaixin LiWataru SekineKosuke OhiraHiroho IshidaAkiko Takenaka-UemaKazuyuki UchidaMasayuki ShimojimaTaisuke HorimotoShin Murakami1Laboratory of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, University of Tokyo13143https://ror.org/057zh3y96, Tokyo, Japan2African Swine Fever Unit, National Agriculture and Food Research Organization (NARO), National Institute of Animal Health34777https://ror.org/051ppg660, Tokyo, Japan3Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo13143https://ror.org/057zh3y96, Tokyo, Japan4Department of Virology I, National Institute of Infectious Diseases13511https://ror.org/001ggbx22, Tokyo, JapanMark T. Heise on June 17, 2025 at 7:00 am
Host origin is a determinant of coevolution between gene segments of avian H9 influenza viruses
by Jennifer E. JonesSeema S. Lakdawala1Department of Microbiology & Molecular Genetics, University of Pittsburgh6614https://ror.org/01an3r305, Pittsburgh, Pennsylvania, USA2Center for Evolutionary Biology and Medicine, University of Pittsburgh607640https://ror.org/01an3r305, Pittsburgh, Pennsylvania, USA3Department of Pediatrics, University of Pittsburgh School of Medicine12317, Pittsburgh, Pennsylvania, USA4Department of Microbiology & Immunology, Emory University197280https://ror.org/03czfpz43, Atlanta, Georgia, USAColin R. Parrish on June 13, 2025 at 7:00 am
Mimivirus transcription and translation occur at well-defined locations within amoeba host cells
by Lotte MayerGeorgi NikolovMartin KunertMatthias HornAnouk Willemsen1Centre for Microbiology and Environmental Systems Science, Division of Microbial Ecology, University of Vienna115351https://ror.org/03prydq77, Vienna, AustriaKristin N. Parent on June 13, 2025 at 7:00 am
Design of SARS-CoV-2 RBD immunogens to focus immune responses toward conserved coronavirus epitopes
by Caitlin HarrisA. Brenda KapingidzaJames E. SanJayani ChristopherTyler GavittBrianna RhodesKatarzyna JanowskaChristopher O'DonnellJared LindenbergerXiao HuangSalam SammourMadison BerryMaggie BarrRob ParksAmanda NewmanMary OvertonThomas OguinPriyamvada AcharyaBarton F. HaynesKevin O. SaundersKevin WieheMihai L. Azoitei1Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA2Department of Cell Biology, Duke University School of Medicine12277, Durham, North Carolina, USA3Department of Medicine, Duke University School of Medicine12277, Durham, North Carolina, USA4Department of Surgery, Duke University School of Medicine12277, Durham, North Carolina, USA5Department of Microbiology and Molecular Genetics, Duke University School of Medicine12277, Durham, North Carolina, USA6Department of Integrative Immunology, Duke University School of Medicine12277, Durham, North Carolina, USA7Department of Biochemistry, Duke University School of Medicine12277, Durham, North Carolina, USAStacey Schultz-Cherry on June 13, 2025 at 7:00 am
MARCH6 suppresses Tembusu virus replication by targeting viral NS5 protein for TOLLIP-mediated selective autophagic degradation
by Peng ZhouWanrong WuJiani WeiYueshan YangAnan JongkaewwattanaYuncai XiaoHui JinHongbo ZhouRui Luo1State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agriculture University124443, Wuhan, China2Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China3Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA)61191https://ror.org/04vy95b61, Pathum Thani, ThailandRebecca Ellis Dutch on June 13, 2025 at 7:00 am
Correction for Lv et al., “Differential antigenic imprinting effects between influenza H1N1 hemagglutinin and neuraminidase in a mouse model”
by Huibin LvQi Wen TeoChang-Chun D. LeeWeiwen LiangDanbi ChoiKevin J. MaoMadison R. ArdaghAkshita B. GopalArjun MehtaMatt SzlembarskiRoberto BruzzoneIan A. WilsonNicholas C. WuChris K. P. Mok on June 12, 2025 at 7:00 am
High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection
by Catherine RexhouseJacob T. BaileySafiehkhatoon MoshkaniJesse L. CiminoMichael D. Robek1Department of Immunology and Microbial Disease, Albany Medical College150552https://ror.org/0307crw42, Albany, New York, USAFelicia Goodrum on June 12, 2025 at 7:00 am
Correction for Gurda et al., “Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8”
by Brittney L. GurdaChristina RauppRuth Popa-WagnerMatthias NaumerNorman H. OlsonRobert NgRobert McKennaTimothy S. BakerJürgen A. KleinschmidtMavis Agbandje-McKenna on June 12, 2025 at 7:00 am