Journal of Virology

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CD4-mimetics sensitize HIV-infected cells to ADCC mediated by plasma from persons with early-stage HIV-1 infection
by Shilei DingAlexandra TauzinDelia Pinto-SantiniSayan DasguptaDerek YangWilliam D. TolbertMonika ChandravanshiMehdi BenlarbiMyriam VerlyJavier R. LamaDonna M. HurynAmos B. SmithMarzena PazgierAndrés FinziAnn Duerr1Centre de Recherche du CHUM177460https://ror.org/04rgqcd02, Montreal, Québec, Canada2Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal5622https://ror.org/0161xgx34, Montreal, Québec, Canada3Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center7286https://ror.org/007ps6h72, Seattle, Washington, USA4Department of Chemistry, School of Arts and Sciences, University of Pennsylvania142839, Philadelphia, Pennsylvania, USA5Infectious Disease Division, Department of Medicine, Uniformed Services University of the Health Sciences1685https://ror.org/04r3kq386, Bethesda, Maryland, USA6Asociación Civil Impacta Salud y Educación585986https://ror.org/02bm24g42, Lima, PeruViviana Simon on July 21, 2025 at 7:00 am
Single-cell RNA sequencing reveals hemocyte heterogeneity, differentiation trajectories, and viral tropism in shrimp (Macrobrachium rosenbergii) infected with decapodiridovirus litopenaeus1
by Bang XiaoFang KangTaolin FanQianqian LiManMan LiuJunming PanJianguo HeChaozheng Li1School of Marine Sciences, State Key Laboratory of Biocontrol /Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-Sen University626303, Guangzhou, P. R. China2Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering/Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-sen University, Sun Yat-Sen University26469, Guangzhou, P. R. China3China-ASEAN Belt and Road Joint Laboratory on Mariculture Technology, Guangzhou, P. R. ChinaMonique M. van Oers on July 18, 2025 at 7:00 am
The intracellular virus-host interface of henipaviruses
by Melanie N. TrippStephen M. RawlinsonSarah J. EdwardsJasmina M. LuczoGlenn A. MarshKim HalpinGregory W. Moseley1Department of Microbiology, Biomedicine Discovery Institute, Monash University161661https://ror.org/02bfwt286, Clayton, Victoria, Australia2Australian Centre for Disease Preparedness, Commonwealth Scientific and Industrial Research Organisation (CSIRO), East Geelong, Victoria, AustraliaSuchetana Mukhopadhyay on July 18, 2025 at 7:00 am
Development of DNA and mRNA-LNP vaccines against an H5N1 clade 2.3.4.4b influenza virus
by Rebecca A. LeonardM. Ariel SpurrierSamantha SkavicusZhaochen LuoBrook E. HeatonRachel L. SprengJiaqi HongFan YuanNicholas S. Heaton1Department of Molecular Genetics and Microbiology, Duke University School of Medicine12277, Durham, North Carolina, USA2Duke Human Vaccine Institute, Duke University School of Medicine12277, Durham, North Carolina, USA3Department of Biomedical Engineering, Duke University242238https://ror.org/00py81415, Durham, North Carolina, USA4Duke Center for Virology, Duke University School of Medicine12277, Durham, North Carolina, USAStacey Schultz-Cherry on July 16, 2025 at 7:00 am
A novel aptamer-based dNTP assay reveals that intact HIV virions are highly stable and do not contain enough dNTPs to support DNA synthesis
by Urja BiswasCynthia BernalRuofan WangJeffrey J. DeStefano1Cell Biology and Molecular Genetics, Bioscience Research Building, University of Maryland1068, College Park, Maryland, USAViviana Simon on July 15, 2025 at 7:00 am
Breadth of antibody activity elicited by an influenza B hemagglutinin vaccine is influenced by pre-existing immune responses to influenza B viruses
by Michael A. CarlockSpencer R. PierceTed M. Ross1Center for Vaccines and Immunology, University of Georgia822673https://ror.org/00te3t702, Athens, Georgia, USA2Florida Research and Innovation Center, Cleveland Clinic587918, Port Saint Lucie, Florida, USA3Department of Infectious Diseases, University of Georgia551782https://ror.org/00te3t702, Athens, Georgia, USA4Department of Infection Biology, Lerner Research Institute, Cleveland Clinic2569https://ror.org/03xjacd83, Cleveland, Ohio, USAAnice C. Lowen on July 15, 2025 at 7:00 am
Rationally designed self-assembled peptide nanofibers provoke robust humoral immunity against nervous necrosis virus
by Chen ZhangYong-Can ZhouWen-Ye SongXin-Xin LiuHai-Hua PengYun Sun1School of Marine Biology and Fisheries, Sanya Institute of Breeding and Multiplication, Collaborative Innovation Center of Marine Science and Technology, Hainan University74629https://ror.org/03q648j11, Haikou, ChinaStacey Schultz-Cherry on July 15, 2025 at 7:00 am
Teaching an old vector new tricks: the surprising versatility of AAV vaccines
by Stephen M. WinstonKristin B. WigginsStacey Schultz-CherryAndrew M. Davidoff1Department of Surgery, St. Jude Children's Research Hospital5417https://ror.org/02r3e0967, Memphis, Tennessee, USA2Department of Host–Microbe Interactions, St. Jude Children's Research Hospital5417https://ror.org/02r3e0967, Memphis, Tennessee, USASuchetana Mukhopadhyay on July 14, 2025 at 7:00 am
The HCMV tegument protein UL88 degrades MyD88 and reduces innate immune activation
by Rinki KumarIrene E. ReiderMadison MartinJulia S. SimpsonNicholas J. BuchkovichChristopher C. Norbury1Department of Cell and Biological Systems, The Pennsylvania State University College of Medicine12310https://ror.org/04p491231, Hershey, Pennsylvania, USADerek Walsh on July 10, 2025 at 7:00 am
Novel insights into immune checkpoints in HIV/SHIV infection: from SHIVSF162P3-infected elite controllers to therapeutic strategy
by Yuting SunChenbo YangPeiwen LiuZhe CongJiahui LuoLing TongJingjing ZhangJiahan LuZiqing JiaLin ZhuQiuhan LuTing ChenQiang WeiDan LiRui HouJing Xue1NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College12501https://ror.org/02drdmm93, Beijing, China2Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, the University of Western Australia569352https://ror.org/047272k79, Perth, Western Australia, Australia3National Center of Technology Innovation for animal model, National Human Diseases Animal Model Resource Center, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences71046https://ror.org/042pgcv68, Beijing, China4Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College12501https://ror.org/02drdmm93, Beijing, China5State Key Laboratory of Respiratory Health and Multimorbidity, Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences71046https://ror.org/042pgcv68, Beijing, China6National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Center for AIDS/ STD Control and Prevention, Chinese Center for Disease Control and Prevention12415https://ror.org/04wktzw65, Beijing, China7Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology) Shenzhen, Guangdong, ChinaViviana Simon on July 10, 2025 at 7:00 am
CX1/BtSY2 and BANAL-20-52 exhibit broader receptor binding and higher affinities to multiple animal ACE2 orthologs than SARS-CoV-2 prototype
by Zepeng XuLinjie LiYuhang GuDedong LiJianxun QiKefang LiuChu-Xia DengGeorge Fu Gao1Faculty of Health Sciences, University of Macauhttps://ror.org/01r4q9n85, Macau SAR, China2Beijing Life Science Academy679188, Beijing, China3CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences85387https://ror.org/00yd0p282, Beijing, China4School of Life Sciences, Yunnan University674423, Kunming, ChinaShan-Lu Liu on July 10, 2025 at 7:00 am
PEDV Nsp14 induces mitophagy-mediated degradation of MAVS to antagonize host innate immunity and facilitate viral proliferation
by Lei YangQisheng QianYan-gang SunXin-xin ChenGuangxu XingJia-qing ZhangBao-song XingSonglin QiaoRui LiGaiping Zhang1College of Veterinary Medicine, Henan Agricultural University731518https://ror.org/04eq83d71, Zhengzhou, Henan, China2Institute for Animal Health, Henan Academy of Agricultural Sciences74728https://ror.org/00vdyrj80, Zhengzhou, Henan, China3Longhu Laboratory693032, Zhengzhou, Henan, China4Henan University of Chinese Medicine232830https://ror.org/02my3bx32, Zhengzhou, Henan, China5Institute of Animal Husbandry, Henan Academy of Agricultural Sciences74728https://ror.org/00vdyrj80, Zhengzhou, Henan, ChinaMark T. Heise on July 9, 2025 at 7:00 am
ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry
by Ruiya LianXueer DouNa WangShasha LiJingying XieXiangrong LiYanmei YangYanqiao WenHuixia LiRuofei Feng1Engineering Research Center of Key Technology and Industrialization of Cell-based Vaccine, Ministry of Education, Biomedical Research Center, Northwest Minzu University66293https://ror.org/04cyy9943, Lanzhou, China2Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University66293https://ror.org/04cyy9943, Lanzhou, China3Gansu Tech Innovation Center of Animal Cell, Biomedical Research Center, Northwest Minzu University66293https://ror.org/04cyy9943, Lanzhou, China4School of Life Sciences and Engineering, Northwest Minzu University66293https://ror.org/04cyy9943, Lanzhou, ChinaTom Gallagher on July 9, 2025 at 7:00 am
Differential decreases in various HIV DNA regions and HIV transcripts after ART initiation during chronic infection
by Julie JanssensCordelia IsbellSun Jin KimAdam WedrychowskiAlton BarbehennRebecca HohSatish K. PillaiMichael J. PelusoSulggi A. LeeTimothy J. HenrichNadia R. RoanSteven G. DeeksSteven A. Yukl1Department of Medicine, University of California, San Francisco (UCSF)8785https://ror.org/043mz5j54, San Francisco, California, USA2Vitalant Research Institute166672, San Francisco, California, USA3Department of Urology, University of California, San Francisco (UCSF)8785https://ror.org/043mz5j54, San Francisco, California, USA4Gladstone Institutes40292https://ror.org/038321296, San Francisco, California, USAShan-Lu Liu on July 8, 2025 at 7:00 am
Targeting papillomavirus infections: high-throughput screening reveals an effective inhibitor of cutaneous β-HPV types
by Ruslan IbragimovSofiya BabokElina Lototskaja-PerepelenkoLarisa IvanovaNika MikhailavaLidiia ZaikinaMarko PiirsooAlla Piirsoo1Institute of Technology, University of Tartu124633https://ror.org/05pyeem08, Tartu, Estonia2Institute of Chemistry, University of Tartu428488, Tartu, Estonia3Institute of Bioengineering, University of Tartu37546https://ror.org/03z77qz90, Tartu, EstoniaKoenraad van Doorslaer on July 8, 2025 at 7:00 am
Phylogenetic analysis of H5N1 influenza viruses isolated from dairy cattle in Texas in December 2024
by Sangam KandelLavanya BabujeeLizheng GuanRandall DahnDavid PattinsonPeter J. HalfmannAmie J. EisfeldGabriele NeumannAlexis C. ThompsonEllen Ruth Alexander MorrisAmy K. SwinfordKeith PoulsenKiril M. DimitrovYoshihiro Kawaoka1Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison5228https://ror.org/01e4byj08, Madison, Wisconsin, USA2Texas A&M Veterinary Medical Diagnostic Laboratory117328, Canyon, Texas, USA3Texas A&M Veterinary Medical Diagnostic Laboratory117328, College Station, Texas, USA4Wisconsin Veterinary Diagnostic Laboratory, University of Wisconsin-Madison5228https://ror.org/01e4byj08, Madison, Wisconsin, USA5Department of Virology, Institute of Medical Science, University of Tokyo26430, Tokyo, Japan6The University of Tokyo Pandemic Preparedness, Infection and Advanced research center (UTOPIA) University of Tokyo13143https://ror.org/057zh3y96, Tokyo, Japan7The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, JapanStacey Schultz-Cherry on July 8, 2025 at 7:00 am
Role of complementary-sense genes and intergenic region of beet curly top virus in intermolecular recombination frequency upon local infection in plants
by Omid EiniZahra ShoaeiNadine SchumannMark Varrelmann1Department of Phytopathology, Institute for Sugar Beet Researchhttps://ror.org/01mdqc612, Göttingen, Germany2KWS SAAT SE & Co KGaA39243, Einbeck, GermanyW. Allen Miller on July 8, 2025 at 7:00 am
Epstein-Barr virus-infected tonsillar marginal zone B cells in vivo as a precursor for immunosuppression-related B-cell lymphoma
by Charles TorgborDavid A. Thorley-LawsonAnn M. Moormann1Tufts University School of Medicine12261https://ror.org/05wvpxv85, Boston, Massachusetts, USA2Department of Medicine, University of Massachusetts Medical School164186https://ror.org/0464eyp60, Worcester, Massachusetts, USALori Frappier on July 8, 2025 at 7:00 am
A novel replication-deficient FCV vaccine provides strong immune protection in cats
by Wuchang HengDan ZangRuiyu LiQian JiangJiasen LiuHonglin JiaHongtao Kang1State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences111613, Harbin, China2Heilongjiang Research Center for Veterinary Biopharmaceutical Technology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences111613, Harbin, ChinaChristiane E. Wobus on July 8, 2025 at 7:00 am
Untangling the causes of geographical disparities in the clinical outcome of HTLV-1 infection: a critical perspective on the contribution of viral genetic diversity
by Thomas DuchateauPhilippe V. AfonsoChloé Journo1Centre International de Recherche en Infectiologie, Retroviral Oncogenesis team, Inserm U1111 - Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, Université Lyonhttps://ror.org/04zmssz18, Lyon, France2Unité Épidémiologie des Virus Oncogènes, Institut Pasteur, Université Paris Cité555089https://ror.org/05f82e368, Paris, FranceDavid E. Levy on July 7, 2025 at 7:00 am